Levamisole Hydrochloride
Synonyms:1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(s)-imidazo(;citarinl;decaris;kw-2-le-t;L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
CAS:16595-80-5
MF:C11H13ClN2S
MW:240.75
EINECS:240-654-6
Chemical Properties:White to almost white crystalline powder
MP:266-267 °C(lit.)
Refractive Index: -126 ° (C=1, H2O)
Water Solubility: 210 g/L (20 ºC)
Usage:Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator. It is an anthelmintic (anti-worm) agent commonly used in large livestock such as cattle, pigs and sheep. Levamisole HCl is used in humans for diseases related to imbalances in the regulation of immune responses or deficiencies of the immune system, including autoimmune diseases, chronic and recurrent diseases, chronic infections and cancer. It has beneficial effects on host defense mechanisms and restores depressed immune responses in animals and humans. Another interesting use of levamisole in humans is as a treatment for common warts (verruca vulgaris).
Packing:As required
Items Standard Results
Characters A white or almost white crystalline powder A white crystalline powder
Identification It complies with the test for specific optical rotation Qualified
IR
gives reaction of chlorides
Appearance of solution Meets the requirements Qualified
PH 3.0～4.5 4.20
Specific optical rotation ﹣121°～﹣128° -122.62°
Related substances Each of impurities A, B, C, D, E≤0.2% A:0.00%, B:0.00% ,C:0.04%, D:0.00%, E:0.01%
Any other impurity ≤0.1% ＜0.1%
Total impurities≤0.3% 0.03%
Heavy metals ≤0.002% ＜0.002%
Loss on drying ≤0.5% 0.10%
Sulphated ash ≤0.1% 0.05%
Assay 98.5%～101.0% 100.1%