Human NODAL Protein, Tag Free
分子別名(Synonym)
NODAL
表達(dá)區(qū)間及表達(dá)系統(tǒng)(Source)
Human NODAL Protein, Tag Free (NOL-H5133) is expressed from E. coli cells. It contains AA His 238 - Leu 347 (Accession # Q96S42).
Predicted N-terminus: Met
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries no "tag".
The protein has a calculated MW of 12.9 kDa. The protein migrates as 14-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 10 mM Sodium citrate, pH3.0 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
該基因編碼TGF-β(轉(zhuǎn)化生長(zhǎng)因子β)超家族蛋白質(zhì)的分泌配體。該家族的配體結(jié)合各種TGF-β受體,導(dǎo)致調(diào)節(jié)基因表達(dá)的SMAD家族轉(zhuǎn)錄因子的募集和激活。編碼的前蛋白經(jīng)過蛋白水解處理,產(chǎn)生調(diào)節(jié)早期胚胎發(fā)育的成熟蛋白。這種蛋白質(zhì)是維持人類胚胎干細(xì)胞多能性所必需的,可能在人類胎盤發(fā)育中發(fā)揮作用。該基因的突變與異位癥有關(guān),這是一種以內(nèi)臟器官相對(duì)于左右軸的隨機(jī)取向?yàn)樘卣鞯募膊 ?/span>
關(guān)鍵字: NODAL;NODAL蛋白;NODAL重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。