CXCL9產(chǎn)品信息

英文名稱：C-X-C motif chemokine 9

中文名稱：C-C基序趨化因子-9

靶點別稱：CXCL9

物種：Human

標簽：His Tag

屬性：Protein

標記：Unconjugated

表達區(qū)間及表達系統(tǒng)（Source）

Human CXCL9 Protein, His Tag (CX9-H51H3) is expressed from E. coli cells. It contains AA Thr 23 - Thr 125 (Accession # Q07325).

Predicted N-terminus: Met

蛋白結(jié)構(gòu)（Molecular Characterization）

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 20.7 kDa. The protein migrates as 17-20 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>90% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, 0.5 M NaCl, 0.5 M Arginine, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

背景（Background）

CXCL9是一種屬于CXC趨化因子家族的小細胞因子，也稱為由γ干擾素（MIG）誘導(dǎo)的單因子。CXCL9是一種在免疫反應(yīng)中起作用的趨化因子，它可以誘導(dǎo)趨化性，促進白細胞的分化和增殖，并導(dǎo)致組織外滲。CXCL9通過與CXCR3受體（如CTL、NK細胞、NKT細胞和巨噬細胞）結(jié)合來調(diào)節(jié)免疫細胞的遷移、分化和激活。CXCL9還參與Th1極化和IFN-γ反應(yīng)。