Human SLAMF1 / SLAM / CD150 Protein, His Tag
分子別名(Synonym)
SLAMF1,CD150,CDw150,SLAM,IPO-3
表達區(qū)間及表達系統(tǒng)(Source)
Human SLAMF1, His Tag (SL1-H52H0) is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Pro 237 (Accession # Q13291-1).
Predicted N-terminus: Ala 21
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 26.2 kDa. The protein migrates as 42-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
信號淋巴細胞活化分子(SLAM)家族的自身配體受體,也稱為CD150,是CD2蛋白家族SLAM亞家族的原型成員。由同型或異型細胞間相互作用觸發(fā)的SLAM受體正在調(diào)節(jié)多種免疫細胞的激活和分化,從而參與先天性和適應(yīng)性免疫反應(yīng)的調(diào)節(jié)和相互連接。活性受小細胞質(zhì)銜接蛋白SH2D1A/SAP和/或SH2D1B/EAT-2存在與否的控制。SLAMF1誘導的T淋巴細胞信號轉(zhuǎn)導事件與B細胞不同。I型跨膜糖蛋白信號淋巴細胞活化分子(SLAM)。
關(guān)鍵字: SLAMF1;SLAMF1蛋白;SLAMF1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。