Human FGF-5 Protein, His Tag (SPR verified)
分子別名（Synonym）
FGF-5,Fibroblast growth factor 5,HBGF-5
表達區(qū)間及表達系統(tǒng)（Source）
Human FGF-5 Protein, His Tag (FG5-H51H3) is expressed from E. coli cells. It contains AA Glu 23 - Gly 268 (Accession # P12034-1).
Predicted N-terminus: Glu 23
蛋白結構（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 29.4 kDa. The protein migrates as 35-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
內毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景（Background）
成纖維細胞生長因子-5（FGF5）是成纖維細胞增長因子（FGF）家族的成員，是頭發(fā)生長的關鍵調節(jié)因子，也是幾種人類癌癥的致癌因子。一般來說，成纖維細胞生長因子5（FGF5）在胚胎組織中廣泛表達，但在成年組織中幾乎不表達。FGF5的過度表達與前列腺癌癥、癌癥、癌癥、腎細胞癌等有關。已證實FGF5通過自分泌和旁分泌作用促進人類星形細胞腦腫瘤的惡性進展。
關鍵字： FGF-5;FGF-5蛋白;FGF-5重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。