Human EDIL3 Protein, Fc Tag
分子別名(Synonym)
DEL1,EDIL3
表達區(qū)間及表達系統(tǒng)(Source)
Human EDIL3, Fc Tag (ED3-H5259) is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Glu 480 (Accession # O43854-1).
Predicted N-terminus: Asp 24
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 77.8 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
EDIL3,也稱為Del1,是一種新型的細(xì)胞外基質(zhì)蛋白,編碼三個Notch樣表皮生長因子重復(fù)序列、一個RGD基序和兩個盤狀結(jié)構(gòu)域。EDIL3在早期發(fā)育過程中以內(nèi)皮細(xì)胞限制性模式表達。EDIL3可能涉及胚胎內(nèi)皮的自分泌血管生成途徑,這一功能部分是通過整合素αVβ3的生產(chǎn)性連接介導(dǎo)的??偟膩碚f,EDIL3在介導(dǎo)血管生成中起著重要作用,可能在血管壁重塑和發(fā)育中起重要作用。此外,它還影響內(nèi)皮細(xì)胞的行為。
關(guān)鍵字: EDIL3;EDIL3蛋白;EDIL3重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。