化合物 Cyclic ADP-ribose|T19253|TargetMol

價格	￥9460
包裝	1mg

最小起訂量	1mg
發(fā)貨地	上海
更新日期	2024-12-12

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產(chǎn)品詳情

中文名稱:化合物 Cyclic ADP-ribose	英文名稱:Cyclic ADP-ribose
CAS:119340-53-3	品牌: TargetMol
產(chǎn)地: 美國	保存條件: Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
產(chǎn)品類別: 抑制劑
貨號: T19253

Product Introduction

Bioactivity

名稱	Cyclic ADP-ribose
描述	Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx caused by the opening of TRPM2 channels.
體外活性	In cells, cyclic ADP ribose (cADPR) plays an important role in the following processes: cell proliferation and differentiation, regulating for example the expansion of mesenchymal stem cells and hematopoietic progenitor cells, neuronal differentiation of PC12 cells and mouse embryonic stem cells Cardiomyocyte differentiation.
體內(nèi)活性	In mammals, cyclic ADP-ribose (cADPR) plays an important role in the following processes: inflammation and immune response, including neutrophil chemotaxis and T cell activation; smooth muscle cell contraction in arteries and bronchial tubes, involved Hypoxic pulmonary vasoconstriction and the pathogenesis of inflammation / allergic airway diseases; myometrial contractility, which ultimately helps delivery; myocardial cell contraction in adult heart tissue, involved in angiotensin II and β-adrenaline Myocardial hypertrophy and arrhythmia caused by isoproterenol; endocrine and exocrine pancreatic secretion; social behavior of mice, including memory formation and spatial learning, are related to oxytocin secretion and may be related to niacin deficiency. In addition, cyclic ADP-ribose (cADPR) is involved in the activation and fertilization of eggs in seaweeds and sea urchins, early development of sea urchins, abscisic acid signaling in sponges and plants, cell fission in dinoflagellates, and pathogenicity of Toxoplasma gondii.
存儲條件	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
關(guān)鍵字	Cyclic ADP?ribose \| Cyclic ADP-ribose \| Cyclic ADP ?ribose
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關(guān)鍵字： cADPR|TargetMol

公司簡介

TargetMol Chemicals Inc. 總部位于馬薩諸塞州波士頓，致力于為全球生化領(lǐng)域科學(xué)家的研究提供專業(yè)的產(chǎn)品和服務(wù)。TargetMol?品牌的客戶群分布于40多個國家和地區(qū)，已發(fā)展成為全球知名的化合物庫和小分子化合物研究供應(yīng)商。 TargetMol?可提供160多種滿足不同需求的化合物庫，以及多種類型的生化試劑產(chǎn)品，包括12000多種抑制劑、16000多種天然產(chǎn)物和各類多肽、抗體、生命科學(xué)試劑盒等，此外，我們還建設(shè)有CADD（計(jì)算機(jī)輔助藥物設(shè)計(jì)）研究中心、藥理實(shí)驗(yàn)室、藥化合成平臺三大技術(shù)中心，全方位滿足客戶的定制需求。憑借我們優(yōu)質(zhì)的產(chǎn)品和服務(wù)、快速高效的全球供應(yīng)鏈和專業(yè)的技術(shù)支持，我們將有效幫助您縮短研發(fā)周期，取得更成功的結(jié)果。

成立日期	2013-04-18 （12年）	注冊資本	566.265100萬人民幣
員工人數(shù)	100-500人	年?duì)I業(yè)額	￥ 1億以上
主營行業(yè)	天然產(chǎn)物,生化試劑,分子生物學(xué),分子砌塊,生物技術(shù)服務(wù)	經(jīng)營模式	貿(mào)易,工廠,試劑,定制,服務(wù)

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公司成立：12年
注冊資本：566.265100萬人民幣
企業(yè)類型：有限責(zé)任公司(自然人投資或控股)
主營產(chǎn)品：小分子抑制劑、藥物篩選化合物庫、藥物篩選等
公司地址：靜安區(qū)江場三路238號8樓

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