4-甲基咪唑

中文名稱：4-甲基咪唑

英文名稱：4-Methylimidazole

CAS   號(hào)：822-36-6

分 子 式：C4H6N2

分 子 量：82.10

結(jié) 構(gòu) 式： 

外    觀：白色至類白色結(jié)晶性粉末

熔    點(diǎn)：54~56℃

密    度：1.02-1.06g/ml

含    量：≥99.5%

用    途：用作環(huán)氧樹脂的固化劑、藥品西咪替丁的主要原料，還可用于合成抗菌劑等。

包    裝：25公斤/紙板桶。

運(yùn)輸貯存：本品貯存運(yùn)輸時(shí)應(yīng)輕裝輕御，防止破損受潮，嚴(yán)禁與有毒品混存。   

檢測(cè)方法：將含有焦糖色素的樣品經(jīng)固相萃取柱（XTR>500 mg）固相萃取，樣品過柱后，用有機(jī)溶劑洗脫，洗脫液濃縮后，用微量點(diǎn)樣器直接在層析材料聚酰胺薄膜上點(diǎn)樣，在裝有相應(yīng)配比的展開劑中上行展開，碘蒸汽顯色后肉眼直接觀察，如果在比移值0.5~0.7之間同時(shí)觀察到比移值與標(biāo)樣相同的棕色斑點(diǎn)，則認(rèn)為該被測(cè)物中含有4-甲基咪唑。

該方法可以實(shí)現(xiàn)快速定性檢測(cè)樣品是天然釀造還是由人工配制，特別適合對(duì)醬油、醋、可樂等含有焦糖色素的樣品進(jìn)行檢測(cè)。展開后的薄層板可長期保存以備復(fù)查，可應(yīng)用薄層掃描儀進(jìn)行測(cè)定。

制備工藝：1、由丙酮醛、乙醛和氨反應(yīng)而得。

          2、以亞硫酸銨為原料生產(chǎn)焦糖色素的過程中產(chǎn)生。

Product Name:4-Methylimidazole 

Another Name:1H-Imidazole, 4-methyl-;1H-Imidazole,4-methyl

CAS No.:822-36-6 

EINECS NO.:212-497-3

Molecular Formula:C4H6N2 

Molecular weight:82.10 

Appearance:Slightly yellow chunks

Purity:≥99.5%

Usage:Imidazole is a heterocyclic compound of five-membered diunsaturated ring structure composed of three carbon atoms and two nitrogen atoms at nonadjacent positions. The simplest member of the imidazole family is imidazole itself, colorless to pale yellow crystalline solid with a weak aminelike odor; soluble in water and alcohol, melts at 89 C, boils at 256 C. Imidazoles are poorly soluble in water generally, but are dissolved in organic solvents, such as chloroform, propylene glycol, and polyethoxylated castor oil. Imidazole ring is found in histidine (an essential amino acid) and histamine, the decarboxylated compound from histamine. Some imidazole compounds inhibit the biosynthesis of ergosterol, required in cell membrane in fungal. They have antibacterial, antifungal, antiprotozoal, and anthelmintic activity. Several distinct phenylimidazoles are therapeutically useful antifungal agents against either superficial or systemic infections. Thiabendazoles which have anthelmintic and antifungal properties are imidazole class compounds. Benzimidazole is a dicyclic compound having midazole ring fused to benzene. Benzimidazole structure is a part of the nucleotide portion of vitamin B12 and the nucleus in some drugs such as proton pump inhibitors and anthelmintic agents. Imidazole has two nitrogen atoms. The one is slightly acidic, while the other is basic. Imidazole and its derivatives are widely used as intermediates in synthesis of organic target compounds including pharmaceuticals, agrochemicals, dyes, photographic chemicals, corrosion inhibitors, epoxy curing agents, adhesives and plastic modifiers.

Packing:25kg/drum