Product Name:Connexin mimetic peptide 40,37GAP26
CAS No.: 514787-21-4
Synonyms:血管連接蛋白 (Cx37、Cx40) 胞外環(huán)多肽
Catalog No.:218P989
Brand:HongTide(上海鴻肽生物)
Description:Connexin mimetic peptide 40,37GAP26是由13個氨基酸組成的多肽,Connexin mimetic peptide 40,37GAP26對應于主要血管連接蛋白 (Cx37、Cx40) 胞外環(huán)的 GAP26 結構域,根據 Cx 同源性指定為 37、40Gap 26。Connexin mimetic peptide 40,37GAP26用于研究間隙連接在環(huán)吡嗪酸 (CPA) 穿過嚙齒動物髂動脈壁引起的內皮超極化擴散中的作用。由 Cx37 和 Cx40 構建的間隙連接斑塊在內皮細胞中含量豐富。Connexin mimetic peptide 40,37GAP26對內膜下超極化具有抑制作用。
Connexin mimetic peptide 40,37GAP26 is a peptide composed of 13 amino acids. Connexin mimetic peptide 40,37GAP26 corresponds to the GAP26 domain of the extracellular loop of major vascular junction proteins (Cx37, Cx40), designated as 37,40Cap 26 based on Cx homology. Connexin mimetic peptide 40,37GAP26 was used to investigate the role of gap junctions in endothelial hyperpolarization diffusion induced by cyclic pyrazine acid (CPA) passing through the iliac artery wall of rodents. The gap junction plaques constructed by Cx37 and Cx40 are abundant in endothelial cells. Connexin mimetic peptide 40,37GAP26 has inhibitory effects on subendothelial hyperpolarization.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | VCYDQAFPISHIR |
Sequence(3-letter code) | H-Val-Cys-Tyr-Asp-Gln-Ala-Phe-Pro-Ile-Ser-His-Ile-Arg-OH |
Peptide Structure |
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Molecular Formula | C70H105N19O19S1 |
Molecular Weight | 1548.76 |
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關鍵字: 514787-21-4;Connexin mimetic pep;血管連接蛋白 (Cx37、Cx40) 胞;多肽生產廠家;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質量作船, 以服務為帆,為科研服務”的企業(yè)理念,為國內外眾多科研工作者提供了優(yōu)質的服務及產品。