對(duì)氟苯腈中文同義詞4-氟苯基氰;4-氟芐腈;4-氟苯甲腈;4-氟苯甲腈,99%;4-氟苯睛;對(duì)氰基氟苯;對(duì)氟苯腈,97+%;對(duì)氟苯加腈英文名稱4-Fluorobenzonitrile英文同義詞PFBN;P-FLUOROBENZONITRILE;Benzonitrile,p-fluoro-(6CI,7CI,8CI);Thefluorinebenzenenitriles;4-Fluorobenzonitrile,97+%;Forfluorobenzonitrile;p-Fluorophenylcyanide;P-FluorobenzonitileCAS號(hào)1194-02-1分子式C7H4FN分子量121.11EINECS號(hào)214-784-9相關(guān)類別氟苯系列;芳烴;醫(yī)藥中間體;硝基和亞硝基化合物;有機(jī)砌塊;有機(jī)原料;醫(yī)用原料;有機(jī)化學(xué);有機(jī)化工原料;有機(jī)中間體;化工原料;原料藥;FluorobenzeneSeries;AromaticNitriles;Fluorobenzene;Nitrile;Nitriles;FluorineCompounds;Benzonitriles(BuildingBlocksforLiquidCrystals);BuildingBlocksforLiquidCrystals;FunctionalMaterials;C6toC7;Cyanides/Nitriles;NitrogenCompounds;Pesticideintermediates;Pyridines;醫(yī)藥原料;化工材料;化工中間體;化學(xué)產(chǎn)品;bc0001;對(duì)照品Mol文件1194-02-1.mol結(jié)構(gòu)式對(duì)氟苯腈性質(zhì)熔點(diǎn)32-34°C(lit.)沸點(diǎn)188°C/750mmHg(lit.)密度1.1070折射率1.4925閃點(diǎn)150°F儲(chǔ)存條件Sealedindry,RoomTemperature溶解度溶于氯仿、乙酸乙酯形態(tài)結(jié)晶低熔點(diǎn)固體顏色白色水溶解性Insolubleinwater.BRN2041517暴露限值NIOSH:IDLH25mg/m3InChIKeyAEKVBBNGWBBYLL-UHFFFAOYSA-NCAS數(shù)據(jù)庫1194-02-1(CASDataBaseReference)NIST化學(xué)物質(zhì)信息Benzonitrile,4-fluoro-(1194-02-1)EPA化學(xué)物質(zhì)信息4-Fluorobenzonitrile(1194-02-1)對(duì)氟苯腈用途與合成方法簡介對(duì)氟苯腈又叫4-氟苯腈,是一種醫(yī)藥中間體,有文獻(xiàn)報(bào)道其可用于制備阿法替尼。阿法替尼二馬來酸鹽于2013年在美國批準(zhǔn)用于治療伴有表皮生長因子受體(EGFR)外顯子19缺失或外顯子21(L858R)替代突變的轉(zhuǎn)移性非小細(xì)胞肺癌(NSCLC)治療。化學(xué)性質(zhì)熔點(diǎn)35-37℃,白色結(jié)晶體。用途醫(yī)藥、農(nóng)藥中間體。用途用作農(nóng)藥、醫(yī)藥中間體
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