中文名稱替拉那韋中文同義詞替拉那韋;N-[3-[(1R)-1-[(6R)-2-羥基-4-氧代-6-苯乙基-6-丙基-5H-吡喃-3-基]丙基]苯基]-5-(三氟甲基)吡啶-2-磺酰胺;替拉那韋雜質(zhì)1;N-(3-((R)-1-((R)-4-羥基-2-氧代-6-苯乙基-6-丙基-5,6-二氫-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡啶-2-磺酰胺;N-(3-((R)-1-((R)-4-羥基-2-氧代-6-苯乙N-(3-((R)-1-((R)-4-羥基-2-氧代-6-苯乙基-6-丙基-5,6-二氫-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡啶-2-磺酰胺基-6-丙基-5,6-二氫-2H-吡喃-3-基)丙基)苯基)-5-(三氟甲基)吡英文名稱Tipranavir英文同義詞Tipranavir(TPV);TIPRANAVIR(PNU-140690);N-[3-[(1R)-1-[(2R)-4-HYDROXY-6-OXO-2-(2-PHENYLETHYL)-2-PROPYL-3H-PYRAN-5-YL]PROPYL]PHENYL]-5-(TRIFLUOROMETHYL)PYRIDINE-2-SULFONAMIDE;PNU-140690;Aptivus;N-[3-[(1R)-1-[(6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide;N-[3-[(1R)-1-[(6R)-2-Hydroxy-4-oxo-6-phenethyl-6-propyl-5H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)pyridine-2-sulfonamide;TipranavirCAS號174484-41-4分子式C31H33F3N2O5S分子量602.66EINECS號相關(guān)類別醫(yī)藥中間體;抗病毒類;AllInhibitors;Inhibitors;Intermediates&FineChemicals;Pharmaceuticals;AntiviralAgentsMol文件174484-41-4.mol

抗病毒藥替拉那韋，西藥名。常用劑型有膠囊劑等。為抗病毒藥。合用利托那韋對具有病毒復(fù)制、并已治療時間很長或感染HIV-1面又耐多種蛋白酶抑制劑的成年患者進(jìn)行治療。生物活性Tipranavir(PNU-1Chemicalbook40690)有效抑制HIV-1蛋白酶酶活性和二聚化，對抗多種蛋白酶抑制劑(PI)的HIV-1分離株具有有效的活性，IC50為66-410nM。靶點IC50:66-410nM(HIV-1isolates)