Human GAS6 (49-678) Protein, His Tag
分子別名(Synonym)
GAS6,GAS-6,AXLLG
表達區(qū)間及表達系統(tǒng)(Source)
Human GAS6 Protein, His Tag (GA6-H5246) is expressed from human 293 cells (HEK293). It contains AA Ala 49 - Ala 678 (Accession # Q14393-2).
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 71.8 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
GAS6(生長停滯特異性蛋白6)也稱為AXL受體酪氨酸激酶配體AXLLG。酪氨酸蛋白激酶受體AXL、TYRO3和MER的配體,其信號傳導(dǎo)與細胞生長和存活、細胞粘附和細胞遷移有關(guān)。GAS6/AXL信號傳導(dǎo)在各種過程中起著重要作用,如酸化過程中的內(nèi)皮細胞存活,通過防止凋亡,人類自然殺傷細胞發(fā)育過程中的最佳細胞因子信號傳導(dǎo),肝再生,促性腺激素釋放激素神經(jīng)元存活和遷移,血小板活化或調(diào)節(jié)血栓反應(yīng)。
關(guān)鍵字: GAS6;GAS6蛋白;GAS6重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。