產(chǎn)品名稱：二氟甲基（2-吡啶基）砜
Product Name：Difluoromethyl (2-pyridyl) sulfone
別名：2-(二氟甲磺酰基)吡啶；2-(二氟甲烷磺酰基)吡啶；胡試劑；2-PySO2CF2H
Alias：2-(Difluoromethylsulfonyl)pyridine;2-[(Difluoromethyl)sulfonyl]pyridine; Difluoromethyl 2-pyridyl sulfone; Hu Reagent; 2-PySO2CF2H
CAS NO：1219454-89-3
分子式(Molecular formula)：C6H5F2NO2S
分子量(Molecular weight)：193.17
理化性質(zhì)：熔點 48-50℃，沸點 324.4±42℃，相對密度 1.423±0.06 g/cm3，微溶于水，易溶于乙腈和甲醇。
Physical and chemical properties: melting point 48-50℃, boiling point 324.4±42℃， relative density 1.423±0.06 g/cm3 , slightly soluble in water, easily soluble in acetonitrile and methanol.
推薦用途：該試劑可用于二氟亞甲基引入，作為偕二氟烯基化試劑與醛和酮反應制備偕二氟烯烴；可用于二氟甲基引入，與芳基鋅、芳基碘反應制備二氟甲基芳基化合物，與烯烴發(fā)生自由基加成反應；可以作為親核二氟（磺化）甲基化試劑，用于從醛、酮、烷基鹵代烴、三氟甲磺酸酯等合成α,α-二氟烷基亞磺酸鹽以及磺酸鹽；還可以與親電碘化試劑和溴化試劑一起使用，用于一碘二氟甲基和一溴二氟甲基引入；還可以用作2-吡啶基化試劑。
Recommended use: This reagent can be used for the introduction of difluoromethylene, as a difluoroalkylation reagent to react with aldehydes and ketones to prepare difluoroalkenes; It can be used for the introduction of difluoromethyl, reacting with aryl zinc and aryl iodine to prepare difluoromethyl aryl compounds, and conducting free radical addition reactions with olefins; It can be used as a nucleophilic difluoro (sulfonation) methylation reagent for synthesis from aldehydes, ketones, alkyl halides, trifluoromethanesulfonic acid esters, etc α,α- Difluoroalkyl sulfinates and sulfonates; It can also be used together with electrophilic iodination reagents and bromination reagents for the introduction of monoiododifluoromethyl and monobromodifluoromethyl; It can also be used as a 2-pyridylation reagent.
關鍵字： 二氟甲基;氟烷基;吡啶基;砜;磺酰基;
山東東岳高分子材料有限公司是東岳集團的全資子公司，成立于2001年，是目前全球裝置規(guī)模最大、品種最全、集科研、生產(chǎn)、經(jīng)營為一體的含氟樹脂、含氟氣體生產(chǎn)企業(yè)，是工信部認證“中國制造業(yè)單項冠軍示范企業(yè)”。擁有9.5萬噸單體和5.5萬噸“塑料王”聚四氟乙烯裝置，生產(chǎn)能力居世界首位，技術和質(zhì)量均躋身世界領先之林。先后承擔了多項國家科技支撐計劃、國家火炬計劃、省市重大科技攻關項目，主持和起草各類標準14項，授權專利118項。