Product Name：Candidalysin
CAS No.：1906866-53-2
Synonyms：細(xì)胞溶解性肽毒素多肽
Catalog No.：218P868
Brand：HongTide（上海鴻肽生物）
Description：Candidalysin 是一種細(xì)胞溶解性肽毒素，最初從 Candida albicans 中分離出來，同時(shí)具有毒性和非毒性的特征，是由31個(gè)氨基酸組成的多肽。Candidalysin 通過與宿主細(xì)胞的上皮生長(zhǎng)因子受體 (EGFR) 相互作用激活上皮細(xì)胞信號(hào)通路，激活基質(zhì)金屬蛋白酶 (MMP) 和鈣離子內(nèi)流，導(dǎo)致炎癥反應(yīng)和免疫細(xì)胞募集。Candidalysin 通過對(duì)宿主細(xì)胞造成膜損傷而表現(xiàn)出細(xì)胞毒性。
Candidalysin is a cell soluble peptide toxin originally isolated from Candida albicans, with both toxic and non-toxic characteristics. It is a peptide composed of 31 amino acids. Candidalysin activates the epithelial signaling pathway by interacting with the host cell's epithelial growth factor receptor (EGFR), activating matrix metalloproteinases (MMPs) and calcium influx, leading to inflammatory response and immune cell recruitment. Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SIIGIIMGILGNIPQVIQIIMSIVKAFKGNK |
Sequence(3-letter code) | H-Ser-Ile-Ile-Gly-Ile-Ile-Met-Gly-Ile-Leu-Gly-Asn-Ile-Pro-Gln-Val-Ile-Gln-Ile-Ile-Met-Ser-Ile-Val-Lys-Ala-Phe-Lys-Gly-Asn-Lys-OH |
Peptide Structure | 
|
Molecular Formula | C153H266N38O38S2 |
Molecular Weight | 3310.11 |
訂購(gòu)聯(lián)系方式：
上海鴻肽生物科技有限公司
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本產(chǎn)品僅供科研使用。
關(guān)鍵字： 1906866-53-2;Candidalysin ;細(xì)胞溶解性肽毒素多肽;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。