Complement Factor D產(chǎn)品信息
英文名稱:Complement factor D
中文名稱:補體因子D
靶點別稱:CFD,Adipsin,PFD
物種:Human/Rhesus macaque/Cynomolgus
屬性:Protein
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally glycerol is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Complement Factor D分子背景
補體因子D(CFD)也被稱為Adipsin、C3轉(zhuǎn)化酶激活劑、Propertin因子D(PFD),它含有一個肽酶S1結(jié)構(gòu)域,屬于肽酶S1家族。當(dāng)因子B與因子C3b復(fù)合時,CFD/Adipsin會裂解因子B,激活C3bbb復(fù)合物,使其成為替代途徑的C3轉(zhuǎn)化酶。CFD/Adipsin是一種絲氨酸蛋白酶,可刺激脂肪細(xì)胞中甘油三酯積累的葡萄糖轉(zhuǎn)運,并抑制脂肪分解。CFD/Adipsin的缺陷是補體因子D缺乏癥的原因,后者易患侵襲性腦膜炎球菌病。
關(guān)鍵字: Complement factor D;補體因子D;CFD蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。