Complement C3a產(chǎn)品信息
英文名稱:Complement Component C3a
中文名稱:補體C3a
靶點別稱:Complement C3a,C3a
物種:Human
屬性:Protein
標記:Biotin-labeled/Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 0.2 M Arginine, PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Complement C3a分子背景
補體C3是血清中的主要補體成分。它主要由巨噬細胞和肝臟合成。C3在補體系統(tǒng)的激活中起著核心作用。C3轉(zhuǎn)化酶對其的處理是經(jīng)典和替代補體途徑的核心反應。它被切割成兩個片段,C3a和C3b。C3a過敏毒素是局部炎癥過程的介質(zhì)。在慢性炎癥中,充當中性粒細胞的化學引誘劑。激活后,C3b可以通過其反應性硫酯與細胞表面碳水化合物或免疫聚集體共價結(jié)合。它誘導平滑肌收縮,增加血管通透性,并導致肥大細胞和嗜堿性白細胞釋放組胺。
關(guān)鍵字: Complement C3a;補體C3a;C3a蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。