Transferrin R2產(chǎn)品信息

別稱：Transferrin R2,TFR2

物種：Human

屬性：Protein

標(biāo)記：Unconjugated

內(nèi)毒素（Endotoxin）

Less than 0.1 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

Transferrin R2分子背景

轉(zhuǎn)鐵蛋白受體蛋白2（TFR2）是一種單程II型膜蛋白，具有蛋白酶相關(guān)（PA）結(jié)構(gòu)域、M28肽酶結(jié)構(gòu)域和轉(zhuǎn)鐵蛋白受體樣二聚化結(jié)構(gòu)域。TFR2基因的突變與遺傳性III型血色素沉著癥有關(guān)。此外，TFR2參與通過(guò)內(nèi)吞作用將轉(zhuǎn)鐵蛋白結(jié)合的鐵攝取到細(xì)胞中，盡管與轉(zhuǎn)鐵蛋白受體1相比，其作用較小。