IL-17 RA & IL-17 RC產(chǎn)品信息
英文名稱:Interleukin-17 receptor A
中文名稱:白細(xì)胞介素-17受體A亞基
靶點(diǎn)別稱:IL-17 RA & IL-17 RC,IL-17RA & IL-17RC,CD217 & IL-17 RC
物種:Human
屬性:Protein/Cell
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70°C for 12 months in lyophilized state from date of receipt;
-70°C for 3 months under sterile conditions after reconstitution.
IL-17 RA & IL-17 RC用戶評(píng)價(jià)
IL-17 RA & IL-17 RC分子背景
由IL17A和IL17F形成的異二聚體,作為與IL17RC的異二元復(fù)合物的一部分。細(xì)胞因子結(jié)合觸發(fā)IL17RA和IL17RC鏈與TRAF3IP2接頭的同型相互作用,導(dǎo)致TRAF6介導(dǎo)的NF-kappa-B和MAP激酶途徑的激活,最終導(dǎo)致細(xì)胞因子、趨化因子、抗菌肽和基質(zhì)金屬蛋白酶的轉(zhuǎn)錄激活,具有潛在的強(qiáng)免疫炎癥。
關(guān)鍵字: IL-17 RA&IL-17 RC;IL-17 RA;IL-17 RC;IL-17 RA蛋白;IL-17 RC蛋白;
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