IgG3 Fc產(chǎn)品信息

英文名稱：Immunoglobulin G

中文名稱：免疫球蛋白G

靶點(diǎn)別稱：IgG3 Fc

物種：Human/Mouse

屬性：Protein

標(biāo)記：Unconjugated

內(nèi)毒素（Endotoxin）

Less than 1.0 EU per μg by the LAL method.

純度（Purity）

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

制劑（Formulation）

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重構(gòu)方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(chǔ)（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

-20°C to -70°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.

IgG3 Fc分子背景

免疫球蛋白G3（IgG3）是許多由有效B細(xì)胞產(chǎn)生和分泌的免疫球蛋白G的成員。在胃蛋白酶切割后，IgG被分成兩個(gè)F（ab），具有一個(gè)抗原結(jié)合位點(diǎn)和一個(gè)高度保守的Fc片段。Fc段具有高度保守的N-糖基化位點(diǎn)。Igγ-3鏈C區(qū)（IgG3 Fc/IGHG3）包含IgG3 H鏈的兩個(gè)恒定區(qū)（CH2、CH3）。