Sortilin產(chǎn)品信息
英文名稱:Sortilin
靶點別稱:Sortilin,SORT1,Glycoprotein 95,Gp95,Gp95LDLCQ6,Neurotensin receptor 3,NT3NTR3,Ntr3,sortilin 1
物種:Human
屬性:Protein/Cell
標(biāo)記:Protein-coupled magnetic beads/Biotin-labeled/Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
Sortilin分子背景
Sortilin是高爾基體隔室中的分選受體,也是細(xì)胞表面的清除受體。通過獨立于甘露糖-6-磷酸受體(M6PR)的途徑將蛋白質(zhì)從高爾基體運輸?shù)饺苊阁w所需。溶酶體蛋白特異性結(jié)合高爾基體中的受體,產(chǎn)生的受體-配體復(fù)合物被轉(zhuǎn)運到酸性前溶酶體室,在那里低pH值介導(dǎo)復(fù)合物的解離。然后,受體通過與逆轉(zhuǎn)錄酶的結(jié)合被再循環(huán)回高爾基體進(jìn)行另一輪運輸。
關(guān)鍵字: Sortilin;Sortilin蛋白;SORT1;SORT1蛋白;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。