GITR產(chǎn)品信息
英文名稱:Glucocorticoid-induced tumor necrosis factor receptor-related protein
中文名稱:糖皮質(zhì)激素誘導(dǎo)的腫瘤壞死因子受體相關(guān)蛋白
靶點(diǎn)別稱:AITR,GITR,TNFRSF18,CD357
物種:Human/Mouse/Cynomolgus
屬性:Protein
標(biāo)記:Unconjugated/Biotin-labeled
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>92% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the
reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
GITR用戶評(píng)價(jià)
GITR分子背景
糖皮質(zhì)激素誘導(dǎo)的TNFR相關(guān)蛋白(GITR)也稱為腫瘤壞死因子受體超家族成員18(TNFRSF18)、活化誘導(dǎo)型TNFR家族受體(AITR)、CD抗原CD357,是腫瘤壞死因子接收器(TNF-R)超家族的成員。GITR是TNFSF18的受體,TNFSF18似乎參與活化的T淋巴細(xì)胞和內(nèi)皮細(xì)胞之間的相互作用以及T細(xì)胞受體介導(dǎo)的細(xì)胞死亡的調(diào)節(jié)。GITR還通過(guò)TRAF2/NIK途徑介導(dǎo)NF-kappa-B的激活。
關(guān)鍵字: GITR;GITR蛋白;CD357;TNFRSF18;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國(guó)生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺(tái)型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國(guó)、美國(guó)、瑞士等12個(gè)城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計(jì)服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長(zhǎng)期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。