Product Name:AF11377
CAS No.:171492-13-0
Synonyms:細(xì)胞因子(cytokine)拮抗劑多肽
Catalog No.:166P07
Brand:HongTide(上海鴻肽生物)
Description:AF11377是由15個(gè)氨基酸組成的直鏈多肽。AF11377可以阻礙 IL-1α 結(jié)合到 I 型 IL-1 受體上,其IC50值為1.9 nM。AF11377可以阻礙人和猴細(xì)胞中 IL-1-驅(qū)動(dòng)的響應(yīng)。AF11377是第一個(gè)高親和力多肽結(jié)合到細(xì)胞因子受體(cytokine receptor)從而作為細(xì)胞因子(cytokine)拮抗劑的例子。
AF11377 is a linear peptide composed of 15 amino acids. AF11377 can hinder IL-1 α When bound to type I IL-1 receptors, its IC50 value is 1.9 nM. AF11377 can hinder the response of IL-1- driven cells in humans and monkeys. AF11377 is the first example of a high affinity peptide binding to a cytokine receptor as a cytokine antagonist.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | FEWTPGYWQPYALPL |
Sequence(3-letter code) | H-Phe-Glu-Trp-Thr-Pro-Gly-Tyr-Trp-Gln-Pro-Tyr-Ala-Leu-Pro-Leu-OH |
Peptide Structure |
|
Molecular Formula | C95H122N18O22 |
Molecular Weight | 1868.12 |
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關(guān)鍵字: AF11377 ;171492-13-0;細(xì)胞因子(cytokine)拮抗劑多肽;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。