| 中文名 | 替卡格雷
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| 英文名 | (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
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| 別名 | 替卡格雷
提卡格雷
替格瑞洛
替卡格雷標(biāo)準(zhǔn)品
替卡格雷及中間體
替卡格雷,替格瑞洛
替卡格雷,替格雷洛,替格瑞洛
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-二氟苯)環(huán)丙基]氨基}-5-(丙基硫氧嘧啶)-3H-[1,2,3]-三唑磷[4,5-D]嘧啶-3-基]-5-(2-羥乙基)環(huán)戊烷-1,2-二醇
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| 英文別名 | Possia
AZD6140
Brilinta
Ticagrelo
Ticagrelor
AR-C126532
Ticargrelor
AR-C 126532XX
Ticagrelor Standards
Ticagrelor and intermediates
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
(1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
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| CAS | 274693-27-5
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| EINECS | 619-540-9 |
| 化學(xué)式 | C23H28F2N6O4S
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| 分子量 | 522.57 |
| InChI | InChI=1/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15?,16?,17-,19-,20+/m0/s1 |
| 密度 | 1.67 |
| 熔點(diǎn) | 138-140°C |
| 沸點(diǎn) | 777.6±70.0 °C(Predicted) |
| 溶解度 | 甲醇 (微溶) |
| 折射率 | 1.744 |
| 酸度系數(shù) | 13.26±0.70(Predicted) |
| 存儲條件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 穩(wěn)定性 | 吸濕性 |
| 外觀 | 固體 |
| 顏色 | White to Off-White |
| 安全術(shù)語 | 24/25 - 避免與皮膚和眼睛接觸。
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| 海關(guān)編號 | 29335990 |
| 下游產(chǎn)品 | 異亞丙基替格瑞洛 |
| 參考資料 查看更多 | 1. Yin, Qiyang, et al. "JLX001 improves myocardial Ischemia-reperfusion injury by activating Jak2-Stat3 pathway." Life S... |