Product Name:ω-Conotoxin MVIIC
CAS No.: 147794-23-8
Synonyms:鈣離子亞型通道多肽OMEGA-CONOTOXIN MVIIC
Catalog No.:211P13
Brand:HongTide(上海鴻肽生物)
Description:ω-Conotoxin MVIIC是具有抑制撲入哺乳動(dòng)物中樞神經(jīng)系統(tǒng)中的其他鈣離子亞型通道的多肽,序列由26個(gè)氨基酸組成,序列中的6個(gè)Cys形成了三對(duì)二硫鍵,多肽結(jié)構(gòu)相當(dāng)穩(wěn)定。ω-Conotoxin MVIIC序列中有四個(gè)Lys,但由于β-折疊的存在,導(dǎo)致側(cè)鏈基團(tuán)被包裹在序列中,因此多肽對(duì)生物素化的反應(yīng)性很多,對(duì)生物活性的影響較小,因此ω-Conotoxin MVIIC具有成為藥物原料的潛能非常巨大。
ω- Conotoxin MVIIC is a peptide that inhibits other calcium ion subtype channels that enter the central nervous system of mammals. The sequence consists of 26 amino acids, and the 6 Cys in the sequence form three pairs of disulfide bonds. The peptide structure is quite stable. ω- There are four Lys in the Conotoxin MVIIC sequence, but due to β- The presence of folding leads to the side chain groups being encapsulated in the sequence, resulting in a high reactivity of peptides towards biotinylation and a relatively small impact on biological activity. Therefore ω- Conotoxin MVIIC has enormous potential as a pharmaceutical raw material.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2(Disulfide bridge:Cys1-Cys16;Cys8-Cys20;Cys15-Cys26) |
Sequence(3-letter code) | H-Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2(Disulfide bridge:Cys1-Cys16;Cys8-Cys20;Cys15-Cys26) |
Peptide Structure |
|
Molecular Formula | C106H178N40O32S7 |
Molecular Weight | 2749.25 |
訂購(gòu)聯(lián)系方式:
上海鴻肽生物科技有限公司
手機(jī): +86-18018095145 (同微信號(hào))
QQ: 3259098395
郵箱:sales1@hongtide.com
關(guān)鍵字: 鈣離子亞型通道多肽OMEGA-CONOT;ω-Conotoxin MVIIC;147794-23-8;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡(jiǎn)稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來(lái),秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。