SLAMF7產(chǎn)品信息
英文名稱:SLAM family member 7
中文名稱:SLAM家族成員-7
靶點(diǎn)別稱:SLAMF7,CD319,CS1,CRACC,19A,FOAP-12
物種:Human / Mouse / Rhesus macaque
屬性:Protein
標(biāo)記:Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-HPLC.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
SLAMF7分子背景
SLAM家族成員7(SLAMF7)也被稱為CD2樣受體激活細(xì)胞毒性細(xì)胞(CRACC)、膜蛋白FOAP-12、CD抗原CD319、新型Ly9、蛋白19A,它是一種單程I型膜蛋白,是CD2家族細(xì)胞表面受體的成員。SLAMF7在脾臟、淋巴結(jié)、外周血白細(xì)胞、骨髓、小腸、胃、闌尾、肺和氣管中表達(dá)。SLAMF7的異構(gòu)體1通過(guò)SH2D1A非依賴性細(xì)胞外信號(hào)調(diào)節(jié)ERK介導(dǎo)的途徑介導(dǎo)NK細(xì)胞活化??赡茉诹馨图?xì)胞粘附中起作用。SLAMF7的異構(gòu)體3不介導(dǎo)任何NK細(xì)胞活化。
關(guān)鍵字: SLAMF7;SLAMF7蛋白;CD319;CD319蛋白;SLAMF7重組蛋白;
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