| 中文名 | 特拉匹韋
|
| 英文名 | Cyclopenta(c)pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydro-, (1S,3aR,6aS)-
|
| 別名 | 特拉匹韋
法匹拉韋
特拉匹韋雜質(zhì)
特拉普韋雜質(zhì)
特拉匹韋-D4
特拉匹韋及中間體
特拉匹韋雜質(zhì)對照品
法匹拉韋 VX950
特拉匹韋(VX-950)
特拉匹韋, 丙型肝炎病毒(HCV)NS3-4A絲氨酸蛋白酶抑制劑
|
| 英文別名 | VX 950
VX-950
MP-424
MP 424
VX-950
LY 570310
TELAPREVIR
VRT-111950
Telaprevir
VRT 111950
UNII-655M5O3W0U
VX-950 (Teleprevir)
(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta[c]pyrrole-1-carboxamide
Cyclopenta(c)pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydro-, (1S,3aR,6aS)-
(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxaMido)acetaMido)-3,3-diMethylbutanoyl)-N-((S)-1-(cyclopropylaMino)-1,2-dioxohexan-3-yl)octahydrocyclopenta[c]pyrrole-1-carboxaMide
(1S,3Ar,6As)-2-((S)-2-((S)-2-Cyclohexyl-2-(Pyrazine-6-Carboxamido)Acetamido)-3,3-Dimethylbutanoyl)-N-((S)-1-(Cyclopropylamino)-1,2-Dioxohexan-3-Yl)-Octahydrocyclopenta[C]Pyrrole-1-Carboxamide
(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-6-carboxamido)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl)-octahydrocyclopenta[c]pyrrole-1-carboxamide VX-950
|
| CAS | 402957-28-2
|
| EINECS | 609-814-6 |
| 化學(xué)式 | C36H53N7O6
|
| 分子量 | 679.85 |
| InChI | InChI=1/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25?,27-,28-,30+/m0/s1 |
| 密度 | 1.25 |
| 熔點(diǎn) | 116-123°C |
| 溶解度 | 氯仿、甲醇 (微溶) |
| 酸度系數(shù) | 11.84±0.20(Predicted) |
| 存儲條件 | Sealed in dry,Store in freezer, under -20°C |
| 外觀 | 固體 |
| 顏色 | Pale Yellow to Light Yellow Waxy to |