MAdCAM-1產(chǎn)品信息
英文名稱:Mucosal addressin cell adhesion molecule-1
中文名稱:黏膜地址素細胞黏附分子-1
靶點別稱:MAdCAM-1,MAdCAM1,Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1
物種:Human
屬性:Protein
標記:Biotin-labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
MAdCAM-1分子背景
粘膜尋址蛋白細胞粘附分子-1(MAdCAM-1)在炎癥性疾病中淋巴細胞向炎癥部位的內(nèi)皮粘附和遷移中起著關(guān)鍵作用。體外和體內(nèi)數(shù)據(jù)表明,阻斷粘附分子-細胞粘附分子中的粘膜尋址(MAdCAM)通路通過抑制MAdCAM與其配體α4β7整合素在淋巴細胞上表達的相互作用,減少白細胞歸巢到腸道。
關(guān)鍵字: MAdCAM1;MAdCAM1蛋白;MAdCAM-1;MAdCAM-1蛋白;黏膜地址素細胞黏附分子1;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。