維百奧生物代理Dendritics公司產(chǎn)品
Dendritics公司主要關(guān)注人類樹突狀細(xì)胞，希望找到能夠促使CD34+造血前體細(xì)胞轉(zhuǎn)化為樹突狀細(xì)胞（在GM-CSF和TNF-alpha存在的情況下）的細(xì)胞因子。在1992-2005年間，大量的研究使得研究者對人類樹突狀細(xì)胞的產(chǎn)生、細(xì)胞通路、C-type凝集素受體的功能及Toll-like受體的活性有了更深的理解。
DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.
Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.
The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.
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關(guān)鍵字： Dendritics;人類樹突狀細(xì)胞;
維百奧（北京）生物科技有限公司成立于2014年，經(jīng)過多年的發(fā)展，已成為一家集生產(chǎn)、銷售、代理、咨詢?yōu)橐惑w的，具有完備的生產(chǎn)、研發(fā)、技術(shù)支持能力，優(yōu)異的售前售后服務(wù)的高新技術(shù)公司。致力于為生命科學(xué)、制藥、診斷、化工、材料、食品、環(huán)境、檢測等行業(yè)的企業(yè)，提供儀器、耗材、試劑、設(shè)備、服務(wù)的一站式服務(wù)。
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