Siglec-10產(chǎn)品信息
英文名稱：Sialic acid-binding Ig-like lectin 10
中文名稱：唾液酸結(jié)合免疫球蛋白樣凝集素-10
靶點(diǎn)別稱：SIGLEC10,MGC126774,PRO940,Siglec10,SLG2
物種：Human / Mouse / Cynomolgus
屬性：Protein
標(biāo)記：Biotin-labeled / Unconjugated / PE Labeled
內(nèi)毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
純度（Purity）
>90% as determined by SDS-PAGE.
制劑（Formulation）
Lyophilized from 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, pH5.5. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
Siglec-10分子背景
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
Siglec-10用戶評(píng)價(jià)
關(guān)鍵字： Siglec-10;Siglec-10蛋白;SIGLEC10;SIGLEC10蛋白;SLG2;
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