Nectin-4產(chǎn)品信息
英文名稱:Nectin-4
中文名稱:細胞黏附分子nectin-4
靶點別稱:NECTIN4,LNIR,PRR4,PVRL4
物種:Human / Mouse / Cynomolgus / Rat
屬性:Protein / Cell / Beads
標記:Biotin-labeled / FITC Labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
Nectin-4分子背景
Nectin-4(基因名PVRL4,脊髓灰質(zhì)炎病毒受體樣4)是一種66kDa的I型跨膜糖蛋白,屬于Ig超家族蛋白Nectin家族。Nectins是細胞粘附分子,在發(fā)育和成年過程中,對上皮細胞、內(nèi)皮細胞、免疫細胞和神經(jīng)元細胞的極性、增殖、分化和遷移等各種生物過程起著關(guān)鍵作用。Nectin-4是一種腫瘤相關(guān)抗原,分別占乳腺癌、卵巢癌和肺癌的50%、49%和86%,主要發(fā)生在預(yù)后不良的腫瘤上。在相應(yīng)的正常組織中未檢測到其表達。
Nectin-4用戶評價
關(guān)鍵字: Nectin4;Nectin4蛋白;Nectin-4;Nectin-4蛋白;細胞黏附分子;
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