中文名：二苯基硼酸-2-氨基乙酯
英文名：2-Aminoethyl diphenylborinate
中文別名：二苯基硼酸
英文別名：524-95-8|2-Aminoethyl diphenylborinate|2-APB|(2-Aminoethoxy)diphenylborane|2-Aminoethoxydiphenylborane|2-((Diphenylboryl)oxy)ethanamine|2-aminoethoxydiphenyl borate|2-Aminoethoxydiphenylborate|2-diphenylboranyloxyethanamine|Borinic acid, diphenyl-, 2-amin
純度：10mM in DMSO
貨號：A424505
包裝：1ml
Cas號：524-95-8
存儲溫度：-80℃儲存
產(chǎn)品介紹：
2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.
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關鍵字： 二苯基硼酸;524-95-8;2-Aminoethyl diphenylborinate;2-APB
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