中文名:CAY10603
英文名:CAY10603
英文別名:CAY10603|1045792-66-2|BML-281|tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate|HDAC6 Inhibitor|tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate|CHEMBL511749|tert-butyl 4-
純度:98%
貨號(hào):H331683
包裝:1mg、100mg、10mg
Cas號(hào):1045792-66-2
存儲(chǔ)溫度:-20°C儲(chǔ)存
產(chǎn)品介紹:
與HDAC1(IC | 50 | = 271 nM),HDAC2(IC | 50 | = 252 nM),HDAC3(IC | 50 |)相比,HDAC6抑制劑是HDAC6(IC | 50 | = 0.002 nM)的選擇性有效抑制劑。 = 0.42 nM),HDAC8(IC | 50 | = 6851 nM)和HDAC10(IC | 50 | = 90.7 nM)。HDAC6抑制劑還阻止了幾種胰腺癌細(xì)胞系的生長(zhǎng)(IC | 50 | = 0.1-1μM )。HDAC6抑制劑在抑制細(xì)胞生長(zhǎng)方面比廣譜HDAC
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