中文名:澤布拉林
英文名:Zebularine
中文別名:1-(β-D-呋喃核糖基)-1,2-二氫嘧啶-2-酮|2-嘧啶酮-1-β- D -核苷|4-脫氧尿苷
英文別名:Zebularine|3690-10-6|4-Deoxyuridine|Pyrimidin-2-one ribonucleoside|Pyrimidin-2-one beta-ribofuranoside|Pyrimidin-2-one beta-D-ribofuranoside|NSC 309132|CHEBI:46938|1-beta-D-ribofuranosyl-2(1H)-pyrimidinone|1-beta-D-ribofuranosylpyrimidin-2(1H)-one|7A9Y5SX
純度:≥98% (HPLC)
貨號(hào):Z135482
包裝:100mg、25mg、5mg
Cas號(hào):3690-10-6
存儲(chǔ)溫度:2-8°C儲(chǔ)存
產(chǎn)品介紹:
Zebularine is a cell-permeable chemically stable cytidine analog and DNA methylation inhibitor which acts by forming a covalent complex with DNMT. It displays antiangiogenic activity and markedly inhibits vessel formation in different tumor models. It reactivates silenced E-cadherin and potentiates the effects of other epigenetic therapeutics such as vorinistat. Induces differentiation of mesenchymal cells into cardiomyocytes. Inhibits cytidine deaminase (CDD).An inhibitor of DNA methyltransferase
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