中文名：毒胡蘿卜素
英文名：Thapsigargin
英文別名：thapsigargin|67526-95-8|Z96BQ26RZD|CHEMBL96926|CHEBI:9516|OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OXY
純度：≥95%
貨號：T135258
包裝：10mg、1mg、5mg
Cas號：67526-95-8
存儲溫度：避光,-20°C儲存,充氬
產(chǎn)品介紹：
Thapsigargin is a cell-permeable sesquiterpene lactone found in the roots of Thapsia garganica. It is a tumor promoter and induces the release of intracellular stored Ca2+ without hydrolysis of inositolphospholipids via inhibition of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA; IC50=30 nM). It may be used to distinguish between discrete intracellular Ca2+ pools. Thapsigargin-induced tumor promotion and down regulation of the EGF receptor is independent of protein kinase C activation.An inducer of stored Ca2+ release.
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關(guān)鍵字： thapsigargin;67526-95-8;Z96BQ26RZD;CHEMBL96926
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