Product Name：Magainin II
CAS No.：108433-95-0
Synonyms：Magainin 2 peptide；蛙皮素2
Catalog No.：112P57
Brand：HongTide（上海鴻肽生物）
Description：Magainin II是一種具有抗菌效果的多肽，由23個(gè)氨基酸組成。研究證明Magainin II具有較強(qiáng)的殺菌效果，主要是通過(guò)誘導(dǎo)大腸桿菌的早期凋亡從而引起其形態(tài)學(xué)改變，進(jìn)而促發(fā)殺菌效果。Magainin II通過(guò)滲透細(xì)胞膜來(lái)殺死細(xì)菌，主要作用機(jī)理是引起細(xì)胞的滲透性腫脹和隨后的細(xì)胞破裂，擾亂負(fù)責(zé)滲透平衡的膜功能，導(dǎo)致細(xì)胞消亡，而Magainin II對(duì)哺乳動(dòng)物細(xì)胞沒(méi)有明顯的毒性。
Magainin II is a peptide with antibacterial properties, composed of 23 amino acids. Research has shown that Magainin II has a strong bactericidal effect, mainly by inducing early apoptosis of Escherichia coli and causing morphological changes, thereby promoting the bactericidal effect. Magainin II kills bacteria by penetrating the cell membrane, mainly by causing osmotic swelling and subsequent cell rupture, disrupting the membrane function responsible for osmotic balance and leading to cell death. However, Magainin II has no significant toxicity to mammalian cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GIGKFLHSAKKFGKAFVGEIMNS |
Sequence(3-letter code) | H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH |
Peptide Structure |  |
Molecular Formula | C114H180N30O29S |
Molecular Weight | 2466.93 |
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關(guān)鍵字： Magainin II ;108433-95-0;Magainin 2 peptide;蛙皮素2;多肽;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。