Rabbit Anti-Phospho-LRP6 (Ser1490) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-LRP6 (Ser1490)
IR:Immunogen Range:P(p-S)PA
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4040
Swiss Prot:O75581
Source:KLH conjugated synthesised phosphopeptide derived from human LRP6 around the phosphorylation site of Ser1490:P(p-S)PA
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-LRP6 (Ser149;LRP6 (Phospho-Ser149;p-LRP6 (S1490);ADCAD2;C030016K15Rik;Cd;FLJ90062;LRP6_HUMAN;
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