Mouse  Anti-LAMP1 Monoclonal Antibody
DATASHEET

Host:Mouse

Target Protein:LAMP1

IR:Immunogen Range:

Clonality:Monoclonal

Isotype:IgG1,k

Entrez Gene:3916

Swiss Prot:P11279

Source:KLH conjugated synthetic peptide derived from human LAMP1: 

Purification:affinity purified by Protein G

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-1000)
ELISA(1:5000-10000)
IF(1:20-200)

Cross Reactive Species:Human
.

"僅供科研使用。不能用于人和動物治療等其它臨床診斷用！