Rabbit  Anti-Phospho-Stat2 (Tyr690) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Phospho-Stat2 (Tyr690)

IR:Immunogen Range:RK(p-Y)LK

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:6773

Swiss Prot:P52630

Source:KLH conjugated Synthesised phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690:RK(p-Y)LK 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Dog
Horse

僅供科研使用。不能用于人和動物治療等其它臨床診斷用！