Rabbit  Anti-Phospho-HSP90 alpha (Thr5 + Thr7) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Phospho-HSP90 alpha (Thr5 + Thr7)

IR:Immunogen Range:EE(p-T)Q(p-T)QD

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:3320

Swiss Prot:P07900

Source:KLH conjugated Synthesised phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5 + Thr7:EE(p-T)Q(p-T)QD 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:In mammalian cells there are at least two Hsp90 isoforms, Hsp90a and Hsp90b which are encoded by separate genes. These ubiquitous and highly conserved proteins account for 1-2% of all cellular proteins in most cells. Hsp90 is part of the cells powerful network of chaperones to fight the deleterious consequences of protein unfolding caused by nonphysiological conditions. However, in the absence of stress, Hsp90 is a necessary component of fundamental cellular processes such as hormone signaling and cell cycle control. In this context several key regulatory proteins such as steriod receptors, cell cycle kinases involved in signal transduction and p53 have been identified as substrates of Hsp90. It has been suggested that Hsp90 acts as a capacitor for morphological evolution by buffering widespread variation, which may affect morphogenic pathways.

Size:50ul

Concentration:1mg/ml

Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species:Human
Mouse
Rat
Pig
Rabbit

僅供科研使用。不能用于人和動物治療等其它臨床診斷用！