Mouse Anti-CEA(C3) Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:CEA(C3)
IR:Immunogen Range:full length
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:1048
Swiss Prot:P06731
Source:KLH conjugated synthetic peptide derived from human CEA/CD66e/CEACAM5:full length
Purification:affinity purified by Protein A
Storage:0.01M PBS(pH7.4) with 0.03% Proclin300 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: CEA(C3);Carcinoembryonic ant;Carcinoembryonic ant;CD66e;CD66e antigen;CEACAM5;DKFZp781M2392;CEAM5_HUMAN;
上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營(yíng)產(chǎn)品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細(xì)胞,原代細(xì)胞 細(xì)胞培養(yǎng)試劑,常用生化試劑。