Rabbit Anti-VPS4B Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:VPS4B
IR:Immunogen Range:301-400/444
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9525
Swiss Prot:O75351
Source:KLH conjugated synthetic peptide derived from human VPS4B:301-400/444
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： VPS4B;8030489C12Rik;Cell migration induc;MGC116271;MIG1;Protein SKD1;Skd1;VPS4B_HUMAN;
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