Rabbit Anti-S1P/Subtilisin isozyme 1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:S1P/Subtilisin isozyme 1
IR:Immunogen Range:861-960/1052
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8720
Swiss Prot:Q14703
Source:KLH conjugated synthetic peptide derived from human S1P/Subtilisin isozyme 1:861-960/1052
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： S1P/Subtilisin isozy;kexin isozyme 1;KIAA0091;MBTPS1;MGC138711;MGC138712;PCSK8;MBTP1_HUMAN;
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