Rabbit Anti-C5R1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:C5R1
IR:Immunogen Range:51-150/350
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:728
Swiss Prot:P21730
Source:KLH conjugated synthetic peptide derived from human C5R1:51-150/350
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Rat
Dog
Pig
Cow
Rabbit
Sheep
Guinea Pig
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： C5R1;ANAPHYLATOXIN RECEPT;C5a anaphylatoxin;C5A;C5aR; CD88 antigen;C5a ligand;C5AR_HUMAN;
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