Rabbit Anti-CH25H Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CH25H
IR:Immunogen Range:1-100/272
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9023
Swiss Prot:O95992
Source:KLH conjugated synthetic peptide derived from human CH25H:1-100/272
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： CH25H;C25H;Cholesterol 25 hydro; Cholesterol 25-hydr;EC 1.14.99.38;h25OH;膽固醇25羥化酶抗體;CH25H_HUMAN;
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