Rabbit Anti-phospho-NCF1 (Ser359) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-NCF1 (Ser359)
IR:Immunogen Range:QR(p-S)K
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:653361
Swiss Prot:P14598
Source:KLH conjugated synthesised phosphopeptide derived from human NCF1 around the phosphorylation site of Ser359:QR(p-S)K
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47-phox and p67-phox. The cytosolic proteins p47-phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47-phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47-phox, suggesting that p47-phox may faciliate the transport of p67-phox to the membrane.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： phospho-NCF1 (Ser359;NCF1 (phospho S359);NOXO2;p47 phox;SH3 and PX domain co;SH3PXD1A;NADPH oxidase p47 ph;NCF1_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學實驗室產(chǎn)品生物科技企業(yè)。主營產(chǎn)品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。