Rabbit Anti-phospho-ADRB2 (Ser346) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-ADRB2 (Ser346)
IR:Immunogen Range:RS(p-S)LK
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:154
Swiss Prot:P07550
Source:KLH conjugated Synthesised phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346:RS(p-S)LK
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關(guān)鍵字: phospho-ADRB2 (Ser34;β2-adrenergic recept;ADRB2R;ADRBR;BAR;B2AR;Catecholamine recept;ADRB2_HUMAN;
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