Rabbit Anti-SLC10A2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:SLC10A2
IR:Immunogen Range:131-230/348
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6555
Swiss Prot:Q12908
Source:KLH conjugated synthetic peptide derived from human ASBT:131-230/348
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SLC10A2 plays a critical role in reabsorption of bile acids from the the small intestine lumen. Passive flow of sodium ions down their concentration gradient is coupled to bile acid movement, resulting in an increase in the concentration of bile acids in the interior of the cell. This action conserves the body's pool of re-circulating bile acid. SLC10A2 also plays a key role in cholesterol metabolism as cholesterol is the precursor molecule in bile acid synthesis mediated by CYP7A and FXR.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： SLC10A2;ASBT;Apical sodium depend;NTCP2;Sodium/taurocholate ;ileal;Solute carrier famil;sodium/bile acid co;
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