Rabbit Anti-EPX Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:EPX
IR:Immunogen Range:601-715/715
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8288
Swiss Prot:P11678
Source:KLH conjugated synthetic peptide derived from human Eosinophil peroxidase heavy chain:601-715/715
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:EPX, eosinophil peroxidase, is an antimycobacterial protein that localizes to cytoplasmic granules of eosinophils and recruits bromide to generate a halogenating oxidant. EPX dependent generation of hypobromous acid causes damage to tissue during inflammatory conditions that include asthma, allergies,cancer and parasitic/helminthic infections. EPX is a major enzyme present in eosinophils and upon degranulation, becomes released into the airways of asthmatics. As a result of its cationic nature and its ability to catalyze the formation of highly toxic oxidants, EPX can induce lung injury in a JNK dependent manner.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： EPX;Eosinophil peroxidas;Eosinophil peroxidas;EPER;EPO;EPP;EPX PEN;PERE_HUMAN;
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