Rabbit Anti-Phospho-IKK alpha (Ser180) + IKK beta (Ser181) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-IKK alpha (Ser180) + IKK beta (Ser181)
IR:Immunogen Range:CT(p-S)FV
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1147
Swiss Prot:O15111
Source:KLH conjugated Synthesised phosphopeptide derived from human IKK alpha/IKK beta around the phosphorylation site of Ser180/Ser181:CT(p-S)FV
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-IKK alpha (S;IKK alpha + IKK beta;p-IKK alpha + IKK be;IkB kinase alpha sub;IKBKA; IKK a kinase;IKK1;IKKA_HUMAN;
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