Rabbit Anti-Urocortin 3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Urocortin 3
IR:Immunogen Range:120-157/161
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:114131
Swiss Prot:Q969E3
Source:KLH conjugated synthetic peptide derived from human UCN3:120-157/161
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Urocortin 3 is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:200-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: Urocortin 3;SCP;SPC;Stresscopin;Ucn III;UCN3;UCNIII;UCN3_HUMAN;
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